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Ultrastructure of Calymmatobacterium granulomatis in Lesions of granuloma inguinale.

Authors
Type
Published Article
Journal
The Journal of infectious diseases
Publication Date
Volume
142
Issue
5
Pages
744–749
Identifiers
PMID: 7462688
Source
Medline
License
Unknown

Abstract

Biopsy specimens from the lesions of 14 patients with granuloma inguinale were examined by electron microscopy. Calymmatobacterium granulomatis, the presumed causative agent, was observed within the phagosomes of many macrophages, but only rarely in polymorphonuclear leukocytes. The morphology of the organisms was that of a gram-negative bacteria having a large capsule and no flagella. These morphologic observations are consistent with published findings suggesting that this organism is related antigenically to organisms of the genus Klebsiella.

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