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The UCSC Cancer Genomics Browser: update 2015.

Authors
  • Goldman, Mary1
  • Craft, Brian2
  • Swatloski, Teresa2
  • Cline, Melissa2
  • Morozova, Olena2
  • Diekhans, Mark2
  • Haussler, David3
  • Zhu, Jingchun1
  • 1 Center for Biomolecular Science and Engineering, University of California at Santa Cruz, Santa Cruz, CA 95064, USA [email protected]
  • 2 Center for Biomolecular Science and Engineering, University of California at Santa Cruz, Santa Cruz, CA 95064, USA.
  • 3 Howard Hughes Medical Institute, University of California at Santa Cruz, Santa Cruz, CA, USA.
Type
Published Article
Journal
Nucleic Acids Research
Publisher
Oxford University Press
Publication Date
January 2015
Volume
43
Issue
Database issue
Identifiers
DOI: 10.1093/nar/gku1073
PMID: 25392408
Source
Medline
License
Unknown

Abstract

The UCSC Cancer Genomics Browser (https://genome-cancer.ucsc.edu/) is a web-based application that integrates relevant data, analysis and visualization, allowing users to easily discover and share their research observations. Users can explore the relationship between genomic alterations and phenotypes by visualizing various -omic data alongside clinical and phenotypic features, such as age, subtype classifications and genomic biomarkers. The Cancer Genomics Browser currently hosts 575 public datasets from genome-wide analyses of over 227,000 samples, including datasets from TCGA, CCLE, Connectivity Map and TARGET. Users can download and upload clinical data, generate Kaplan-Meier plots dynamically, export data directly to Galaxy for analysis, plus generate URL bookmarks of specific views of the data to share with others.

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