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Typhoid vaccines

Authors
  • Aggarwal, Anju1
  • Dutta, A. K.1
  • 1 ESI Hospital, Lady Hardinge Medical College and Kalawati Saran Children's Hospital, Basaidarapur, 3 Lady Hardinge Medical College Campus, New Delhi, 110001 , New Delhi
Type
Published Article
Journal
The Indian Journal of Pediatrics
Publisher
Springer-Verlag
Publication Date
Aug 01, 2001
Volume
68
Issue
8
Pages
733–736
Identifiers
DOI: 10.1007/BF02752413
Source
Springer Nature
Keywords
License
Yellow

Abstract

Typhoid fever continues to be a major public health problem in developing countries with about 33 million cases per year. Protective efficacy of traditional acetone/phenol killed vaccines is similar to newer typhoid vaccines (Ty21A and Vi antigen vaccine) but side effects of these newer vaccines are considerably less. Though the mortality is low, typhoid fever causes considerable morbidity and loss of working days. Problems during treatment are increasing due to emergence and spread of multidrug resistant S. typhi. Hence to decrease the incidence of typhoid fever in addition to ensuring safe water supply and excreta disposal a typhoid vaccine needs to be introduced in the National Immunization Schedule.

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