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Two-arm randomized pilot intervention trial to decrease sitting time and increase sit-to-stand transitions in working and non-working older adults

  • Kerr, Jacqueline
  • Takemoto, Michelle
  • Bolling, Khalisa
  • Atkin, Andrew
  • Carlson, Jordan
  • Rosenberg, Dori
  • Crist, Katie
  • Godbole, Suneeta
  • Lewars, Brittany
  • Pena, Claudia
  • Merchant, Gina
Publication Date
Jan 06, 2016
Apollo - University of Cambridge Repository
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Background: Excessive sitting has been linked to poor health. It is unknown whether reducing total sitting time or increasing brief sit-to-stand transitions is more beneficial. We conducted a randomized pilot study to assess whether it is feasible for working and non-working older adults to reduce these two different behavioral targets. Methods: Thirty adults (15 workers and 15 non-workers) age 50–70 years were randomized to one of two conditions (a 2-hour reduction in daily sitting or accumulating 30 additional brief sit-to-stand transitions per day). Sitting time, standing time, sit-to-stand transitions and stepping were assessed by a thigh worn inclinometer (activPAL). Participants were assessed for 7 days at baseline and followed while the intervention was delivered (2 weeks). Mixed effects regression analyses adjusted for days within participants, device wear time, and employment status. Time by condition interactions were investigated. Results: Recruitment, assessments, and intervention delivery were feasible. The ‘reduce sitting’ group reduced their sitting by two hours, the ‘increase sit-to-stand’ group had no change in sitting time (p < .001). The sit-to-stand transition group increased their sit-to-stand transitions, the sitting group did not (p < .001). Conclusions: This study was the first to demonstrate the feasibility and preliminary efficacy of specific sedentary behavioral goals. / The pilot study was supported by funds provided by the Department of Family Medicine & Public Health, UCSD. The work of Andrew J Atkin was supported by the Centre for Diet and Activity Research (CEDAR), a UKCRC Public Health Research Centre of Excellence (RES-590-28-0002). Funding from the British Heart Foundation, Department of Health, Economic and Social Research Council, Medical Research Council, and the Wellcome Trust, under the auspices of the UK Clinical Research Collaboration, is gratefully acknowledged. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. / This is the final version of the article. It was first available from PLOS via

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