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Two milligrams i.v. hydromorphone is efficacious for treating pain but is associated with oxygen desaturation.

Authors
  • Chang, Andrew K1
  • Bijur, Polly E
  • Napolitano, Antonio
  • Lupow, Jason
  • Gallagher, E John
  • 1 Department of Emergency Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA.
Type
Published Article
Journal
Journal of opioid management
Publication Date
Jan 01, 2009
Volume
5
Issue
2
Pages
75–80
Identifiers
PMID: 19507803
Source
Medline
License
Unknown

Abstract

Two milligrams i.v. hydromorphone provides efficacious and rapid pain relief in nonelderly adults presenting to the ED with acute severe pain. However, oxygen desaturation below 95 percent occurred in about one third of patients. Although no noticeable clinical signs of hypoxemia occurred, a conservative interpretation of this finding suggests that 2 mg i.v. hydromorphone is too much opioid to be given routinely to patients in pain as a single initial dose.

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