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Two-dimensional and quasi-three-dimensional dosimetry of hadron and photon beams with the Magic Cube and the Pixel Ionization Chamber.

Authors
  • Cirio, R
  • Garelli, E
  • Schulte, R
  • Amerio, S
  • Boriano, A
  • Bourhaleb, F
  • Coutrakon, G
  • Donetti, M
  • Giordanengo, S
  • Koss, P
  • Madon, E
  • Marchetto, F
  • Nastasi, U
  • Peroni, C
  • Santuari, D
  • Sardo, A
  • Scielzo, G
  • Stasi, M
  • Trevisiol, E
Type
Published Article
Journal
Physics in medicine and biology
Publication Date
Aug 21, 2004
Volume
49
Issue
16
Pages
3713–3724
Identifiers
PMID: 15446800
Source
Medline
License
Unknown

Abstract

Two detectors for fast two-dimensional (2D) and quasi-three-dimensional (quasi-3D) verification of the dose delivered by radiotherapy beams have been developed at University and Istituto Nazionale di Fisica Nucleare (INFN) of Torino. The Magic Cube is a stack of strip-segmented ionization chambers interleaved with water-equivalent slabs. The parallel plate ionization chambers have a sensitive area of 24 x 24 cm2, and consist of 0.375 cm wide and 24 cm long strips. There are a total of 64 strips per chamber. The Magic Cube has been tested with the clinical proton beam at Loma Linda University Medical Centre (LLUMC), and was shown to be capable of fast and precise quasi-3D dose verification. The Pixel Ionization Chamber (PXC) is a detector with pixel anode segmentation. It is a 32 x 32 matrix of 1024 cylindrical ionization cells arranged in a square 24 x 24 cm2 area. Each cell has 0.4 cm diameter and 0.55 cm height, at a pitch of 0.75 cm separates the centre of adjacent cells. The sensitive volume of each single ionization cell is 0.07 cm3. The detectors are read out using custom designed front-end microelectronics and a personal computer-based data acquisition system. The PXC has been used to verify dynamic intensity-modulated radiotherapy for head-and-neck and breast cancers.

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