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Two Different Concentrations of Topical Levofloxacin for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Keratitis.

Authors
  • Tajima, Kazuki1, 2
  • Miyake, Taku1
  • Koike, Naohito3
  • Hattori, Takaaki1
  • Takahashi, Hiroki1
  • Matsumoto, Tetsuya3
  • Fujita, Koji4
  • Kuroda, Masahiko4
  • Ito, Norihiko1, 5
  • Goto, Hiroshi1
  • 1 1 Department of Ophthalmology, Tokyo Medical University , Tokyo, Japan . , (Japan)
  • 2 2 Department of Surgery, Keio University , Tokyo, Japan . , (Japan)
  • 3 3 Department of Microbiology, Tokyo Medical University , Tokyo, Japan . , (Japan)
  • 4 4 Department of Molecular Pathology, Tokyo Medical University , Tokyo, Japan . , (Japan)
  • 5 5 University Veterinary Medical Center, Tottori University , Tottori, Japan . , (Japan)
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
Dec 01, 2015
Volume
31
Issue
10
Pages
636–641
Identifiers
DOI: 10.1089/jop.2015.0026
PMID: 26348840
Source
Medline
License
Unknown

Abstract

Using our MDRP keratitis model, we showed that topical 0.5% levofloxacin is not adequately effective, while 1.5% levofloxacin is efficacious in controlling MDRP keratitis.

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