[Tumors of the inner ear and adjacent structures].
Abteilung Neuropathologie, Department für Pathologie und Neuropathologie und Zentrum für Neuroonkologie, Comprehensive Cancer Center, Universitätsklinikum Tübingen, Eberhard-Karls-Universität Tübingen, Calwerstr. 3, 72076, Tübingen, Deutschland. [email protected]
- Published Article
- Publication Date
Nov 01, 2017
Tumors of the inner ear and adjacent structures often present with hearing loss, tinnitus and vertigo due to compression of the traversing cranial nerves. More than 90% of the tumors of the inner ear with or without expansion into the cerebellopontine angle are histologically diagnosed as vestibular schwannomas. Less common tumorous lesions include ectopic meningiomas located in the petrous bone, glomus tympanicum paragangliomas or endolymphatic sac tumors (ELST) originating in the vestibular recess. Most tumors are sporadic, but hereditary disorders have to be considered. Bilateral vestibular schwannomas are indicative of neurofibromatosis type 2 and ELST in conjunction with other abdominal tumors indicates von Hippel-Lindau disease. The neuropathological diagnostics and grading guides the subsequent therapy of these mostly benign lesions.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/28875382