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Troglitazone-induced liver failure: a case study.

Authors
  • Graham, David J
  • Green, Lanh
  • Senior, John R
  • Nourjah, Parivash
Type
Published Article
Journal
The American Journal of Medicine
Publisher
Elsevier
Publication Date
Mar 01, 2003
Volume
114
Issue
4
Pages
299–306
Identifiers
PMID: 12681458
Source
Medline
License
Unknown

Abstract

The progression to irreversible liver injury probably occurred within a 1-month interval in most patients, casting doubt on the value of monthly monitoring of serum aminotransferase levels as a means of preventing troglitazone-induced acute liver failure. The cumulative risk of hepatic failure increased with continued use.

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