Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound.

Authors
  • 1
  • 1 Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA 02215.
Type
Published Article
Journal
Advanced healthcare materials
2192-2659
Publication Date
Volume
2
Issue
9
Pages
1204–1208
Identifiers
DOI: 10.1002/adhm.201200381
PMID: 23592698
Source
Medline
Keywords
License
Unknown

Abstract

Application of high-intensity focused ultrasound to drug-loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B-mode imaging. Drug-loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment.

Statistics

Seen <100 times