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Trichilone, a new C21 steroid from Trichilia connaroides.

Authors
  • Zhang, Qiang
  • Zhang, Yu
  • He, Hong-Ping
  • Di, Ying-Tong
  • Hao, Xiao-Jiang
Type
Published Article
Journal
Natural product communications
Publication Date
Oct 01, 2012
Volume
7
Issue
10
Pages
1267–1268
Identifiers
PMID: 23156985
Source
Medline
License
Unknown

Abstract

Phytochemical investigation of the leaves of Trichilia connaroides led to the isolation of a new pregnane, trichilone (1), featuring a 2-methoxycyclopent-2-enone moiety, along with a related known compound, 3beta,4alpha-dihydroxypregnane-16-one (2). The structure of 1 was established on the basis of extensive spectroscopic analysis. Compound 1 showed significant root-growth inhibition activity against Amaranthus. mangostanus with an IC50 value of 23.1 ppm.

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