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TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion.

Authors
  • Prudente, S
  • Baratta, R
  • Andreozzi, F
  • Morini, E
  • Farina, M G
  • Nigro, A
  • Copetti, M
  • Pellegrini, F
  • Succurro, E
  • Di Pietrantonio, L
  • Brufani, C
  • Barbetti, F
  • Dallapiccola, B
  • Sesti, G
  • Trischitta, V
  • Frittitta, L
Type
Published Article
Journal
Diabetologia
Publisher
Springer-Verlag
Publication Date
Jul 01, 2010
Volume
53
Issue
7
Pages
1354–1361
Identifiers
DOI: 10.1007/s00125-010-1749-1
PMID: 20393693
Source
Medline
License
Unknown

Abstract

Our data confirm that the TRIB3 R84 variant affects glucose homeostasis and suggest this effect is due to an alteration of the interplay between insulin sensitivity and secretion.

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