Affordable Access

Treponema-specific and antilipoidal 19S(IgM) antibodies in penicillin-treated and untreated rabbits after infection with Treponema pallidum.

Authors
Type
Published Article
Journal
The British journal of venereal diseases
Publication Date
Volume
57
Issue
1
Pages
15–19
Identifiers
PMID: 7008895
Source
Medline

Abstract

The titres of treponema-specific and antilipoidal 19S(IgG) antibodies were determined in rabbits infected intratesticularly with Treponema pallidum. One group of rabbits was treated with penicillin the other served as control. Using different serological tests it was shown that 19S(IgM) antibodies were still detectable eight months after infection at about the same titres in both groups. In contrast, 19S(IgM) antibody titres in patients with syphilis became undetectable within three to six months after penicillin treatment. It is suggested therefore that the rabbit is not a reliable model for studying the effect of penicillin in human T pallidum infections.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments