Mixt. 716 is composed of traditional Chinese medicinal herbs, including Oldenlandia diffusa, Euphorbia humifusa, Onychium japonicum, Acalypha australis. 150 cases of upper respiratory infection were divided into 716 treatment group (89 cases) and control group (61 cases) randomly. The effective rate was 92% in treatment group compared with 67% in control group. Experimental studies also showed that Mixt. 716 was slightly cytotoxic, it could obviously inhibit influenza virus A.