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Treatment of tuberculosis infection complicated with liver transplant

Authors
  • Qiu, Ju
  • Liu, Sibo
  • Wang, Qian
Type
Published Article
Journal
Infection International
Publisher
Sciendo
Publication Date
Sep 30, 2018
Volume
7
Issue
3
Pages
81–87
Identifiers
DOI: 10.2478/ii-2018-0025
Source
De Gruyter
Keywords
License
Green

Abstract

Liver transplant is considered the best choice for treating various end-stage liver diseases either at home or abroad. Among patients of liver transplant complicated with tuberculosis (TB), the incidence and mortality of postoperative active TB are bound to increase remarkably. Diagnosing and treating TB in patients with end-stage liver diseases who received immunosuppressants after liver transplant are difficult because of the absence of specific clinical manifestations while being complicated with TB, reduced sensitivity to cellular immunoassay, and interaction between anti-TB drugs and immunosuppressants. Therefore, the screening of high-risk groups, improvement in diagnostic accuracy, preoperative treatment, and reduced interaction between anti-TB drugs and immunosuppressants can help optimize diagnosis and treatment regimes and thus further improve the prognosis of patients.

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