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Treatment of pseudohypoparathyroidism with 1 alpha-hydroxyvitamin D3.

Authors
Type
Published Article
Journal
Contributions to Nephrology
0302-5144
Publisher
S. Karger AG
Publication Date
Volume
22
Pages
68–73
Identifiers
PMID: 7398339
Source
Medline
License
Unknown

Abstract

A maintenance dosis of 2 microgram/day of 1 alpha-OH-D3 could keep the level of serum calcium normal in all 5 cases with pseudohypoparathyroidism, in contrast with 4.0 +/- 1.26 microgram/day needed for the 11 cases with hypoparathyroidism (8 idiopathic and 3 postoperative). The conspicuous effect of 1 alpha-OH-D3 on pseudohypoparathyroidism is likely to be attributed to the fact that the unresponsiveness of bone tissue to parathyroid hormone is corrected by the action of active vitamin D.

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