Based on a personal experience of the treatment of venous insufficiency of low extremities, was selected a group of 31 patients from 167 patients with trophic disorders resulted from venous insufficiency of low extremities. The patients of the selected group had along typical venous insufficiency related symptoms a neurological syndrome which was typical for the tarsal canal. Neurological disorders in 26 patients may be caused by a long persisting ulcer and chronic regional inflammation against venous hypertension. The syndrome of the tarsal canal in 5 patients may develop as recurrence of venous disease following the surgical operation after Linton. The patients of the selected group underwent final correction of venous hemodynamics, decompression and neurolysis of posterior tibial nerve in the tarsal canal.