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Treatment of intraoperative hypotension with cafedrine/theodrenaline versus ephedrine : A prospective, national, multicenter, non-interventional study-the HYPOTENS trial.

Authors
  • Eberhart, L1
  • Geldner, G2
  • Kowark, A3
  • Zucker, T-P4
  • Kreuer, S5
  • Przemeck, M6
  • Huljic, S7
  • Koch, T8
  • Keller, T9
  • Weber, S9
  • Kranke, P10
  • 1 Department of Anesthesiology & Intensive Care, Philipps University Marburg, Baldingerstraße 1, 35033, Marburg, Germany. [email protected] , (Germany)
  • 2 Clinic for Intensive Care, Emergency Medicine and Pain Therapy, Hospital Ludwigsburg, Ludwigsburg, Germany. , (Germany)
  • 3 Department of Anesthesiology, Medical Faculty, RWTH Aachen University, Aachen, Germany. , (Germany)
  • 4 Department of Anesthesiology, Intensive Care and Pain Therapy, Academic Teaching Hospital Traunstein, Traunstein, Germany. , (Germany)
  • 5 Department of Anesthesiology, Intensive Care and Pain Therapy, University Hospital Saarland, Homburg, Germany. , (Germany)
  • 6 Department of Anesthesiology and Intensive Care, DIAKOVERE Annastift, Hannover, Germany. , (Germany)
  • 7 ratiopharm GmbH, Ulm, Germany. , (Germany)
  • 8 Department of Anesthesiology & Intensive Care, Philipps University Marburg, Baldingerstraße 1, 35033, Marburg, Germany. , (Germany)
  • 9 ACOMED Statistik, Leipzig, Germany. , (Germany)
  • 10 Department of Anesthesia and Critical Care, University Hospital Würzburg, Würzburg, Germany. , (Germany)
Type
Published Article
Journal
Der Anaesthesist
Publisher
Springer-Verlag
Publication Date
Apr 01, 2021
Volume
70
Issue
4
Pages
298–307
Identifiers
DOI: 10.1007/s00101-020-00877-5
PMID: 33170310
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Hinsichtlich der Kreislaufstabilisierung war keine der beiden Therapieoptionen überlegen. Post-hoc-Analysen deuten darauf hin, dass C/T unter Routinebedingungen eine zielorientiertere und einfacher zu steuernde Kreislaufstabilisierung ermöglicht. Die seltener erforderlichen erweiterten Therapiemaßnahmen zur ergänzenden IOH-Korrektur stellen einen möglichen Grund für die höhere Anwenderzufriedenheit dar.

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