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[Treatment of duodenal ulcers with antacid mixtures and sulpiride. A double-blind controlled study (author's transl)].

Authors
  • Lam, S K
  • Lam, K C
  • Lai, C L
  • Yeung, C K
  • Yam, L Y
  • Wong, W S
Type
Published Article
Journal
La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Publication Date
Jan 01, 1978
Volume
54
Issue
43-44
Pages
1404–1407
Identifiers
PMID: 219500
Source
Medline
License
Unknown

Abstract

A total of 108 patients with duodenal ulcers were divided into 4 groups in a double-blind study controlled by endoscopic examinations. Patients in each group were given either an antacid mixture or sulpiride alone, antacid mixture plus sulpiride, or a placebo. The highest complete recovery rate (84 per cent) was noted in the antacid mixture plus sulpiride group, while partial healing (more than 50 per cent reduction in ulcer size) was highest in the sulpiride group (84,6 per cent). As sulpiride has both healing effects on the ulcer and an analgesic effect against pain it can be prescribed in association with antacid mixtures for the treatment of duodenal ulcers.

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