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Treatment of Cushing's disease with bilateral adrenalectomy and autotransplantation.

Authors
Type
Published Article
Journal
Hormone research
Publication Date
Volume
13
Issue
2
Pages
81–89
Identifiers
PMID: 7227977
Source
Medline
License
Unknown

Abstract

2 Cases of childhood Cushing's disease have been treated with bilateral adrenalectomy and autotransplantation of adrenal tissue. Transplantation was unsuccessful in 1 case. In the other patient, replacement therapy was discontinued without any symptoms of hypo- or hyperadrenocorticism. Her urinary 17-hydroxycorticosteroids, free cortisol and aldosterone remain in the low normal range indicating functional adrenal tissue, probably a result of the transplant.

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