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[Treatment of antiphospholipid syndrome].

Authors
Type
Published Article
Journal
Revista de medicina de la Universidad de Navarra
Publication Date
Volume
51
Issue
4
Pages
38–41
Identifiers
PMID: 18303659
Source
Medline
License
Unknown

Abstract

The antiphospholipid syndrome (APS) is a disorder of recurrent thrombosis and/or pregnancy loss associated with the presence of antiphospholipid antibodies and persistently positive lupus anticoagulant, anticardiolipin or anti beta2-glycoprotein1. Oral anticoagulants are the best available and most effective treatment for the secondary prevention of recurrent venous or arterial thrombosis. Patients with APS are treated with long-term therapy to prolong the INR to 2.0-3.0. Low-molecular-weight heparin in combination with low-aspirin dose is a reasonable strategy to avoid pregnancy loss in women with this syndrome.

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