Affordable Access

Treatment of ABO hemolytic disease with synthetic blood group trisaccharides.

Authors
Type
Published Article
Journal
Vox sanguinis
Publication Date
Volume
66
Issue
3
Pages
194–199
Identifiers
PMID: 8036789
Source
Medline
License
Unknown

Abstract

Thirteen infants, 10 with A-O and 3 with B-O hemolytic disease of the newborn (ABO-HDN), were treated with synthetic A or B blood group trisaccharides (ATS, BTS) which cause dissociation of maternal antibody bound to infant red cells. The clinical outcome was compared with that of a control group of 21 infants treated with phototherapy during the preceding year. Exchange transfusion was required in 2 out of 13 infants in the experimental group and in 7 in the control group. A randomized prospective controlled study is necessary to confirm these results.

Statistics

Seen <100 times