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Transplantation of VEGF165-gene-transfected endothelial progenitor cells in the treatment of chronic venous thrombosis in rats.

Authors
  • Meng, Qing-you1
  • Li, Xiao-qiang
  • Yu, Xiao-bin
  • Lei, Feng-rui
  • Jiang, Kun
  • Li, Chuan-yong
  • 1 Department of Vascular Surgery, Second Affiliated Hospital of Suzhou University, Suzhou, Jiangsu 215004, China. , (China)
Type
Published Article
Journal
Chinese medical journal
Publication Date
Feb 20, 2010
Volume
123
Issue
4
Pages
471–477
Identifiers
PMID: 20193489
Source
Medline
License
Unknown

Abstract

The EPCs were successfully transfected by Ad-VEGF165. A suitable transfection ratio can improve the efficiency of EPCs and the possibility of promotion of angiogenesis after transplantation. Transfected EPCs caused accelerated organization and recanalization of vein thrombi.

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