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[Transmural heterogeneity of calcium handling proteins in the mechanism of porcine model of ventricular fibrillation].

Authors
  • Lü, Jing-jun
  • Lin, Guo-sheng
  • Zhao, Dong-dong
  • Cui, Bo
  • Wei, Jie
  • Bao, Ming-wei
Type
Published Article
Journal
Zhonghua xin xue guan bing za zhi
Publication Date
Apr 01, 2008
Volume
36
Issue
4
Pages
355–359
Identifiers
PMID: 19100017
Source
Medline
License
Unknown

Abstract

It has been shown that Calcium cycling could modulate APD restitution property in the intact heart. The interaction between action potential and calcium dynamics instabilities is one of the most important reasons why simple criterion such as the APD restitution slope > 1 may fail to accurately predict the onset of APD alternans.

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