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A translocation between 3q21 and 12q24 in a patient with minimally differentiated acute myeloid leukemia (AML-M0).

Authors
  • Yamagata, N
  • Shimazaki, C
  • Kikuta, T
  • Hirai, H
  • Sumikuma, T
  • Sudo, Y
  • Ashihara, E
  • Goto, H
  • Inaba, T
  • Fujita, N
  • Nakagawa, M
Type
Published Article
Journal
Cancer Genetics and Cytogenetics
Publisher
Elsevier
Publication Date
Sep 01, 1997
Volume
97
Issue
2
Pages
90–93
Identifiers
PMID: 9283587
Source
Medline
License
Unknown

Abstract

Only a small number of reports have described the cytogenetic analysis of minimally differentiated acute myeloid leukemia (AML, M0). We performed a cytogenetic analysis on a patient with AML (M0) with a normal platelet count. It revealed a chromosomal translocation between chromosome bands 3q21 and 12q24. 3q. Abnormalities in AML are known to be associated with normal or elevated platelet counts. 3q21 and 12q24 are common translocation sites in AML patients, but this is the first report of translocation t(3;12)(q21;q24) in an AML patient.

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