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Transfusion-related acute lung injury and potential risk factors among the inpatient US elderly as recorded in Medicare claims data, during 2007 through 2011.

Authors
  • Menis, Mikhail
  • Anderson, Steven A
  • Forshee, Richard A
  • McKean, Stephen
  • Johnson, Chris
  • Warnock, Rob
  • Gondalia, Rahul
  • Mintz, Paul D
  • Holness, Leslie
  • Worrall, Christopher M
  • Kelman, Jeffrey A
  • Izurieta, Hector S
Type
Published Article
Journal
Transfusion
Publication Date
Sep 01, 2014
Volume
54
Issue
9
Pages
2182–2193
Identifiers
DOI: 10.1111/trf.12626
PMID: 24673344
Source
Medline
License
Unknown

Abstract

Our study among the elderly suggests TRALI to be a severe event and identifies a substantially increased TRALI occurrence with greater number of units and with PLT- or plasma-containing transfusions. The study also suggests importance of underlying health conditions, prior recipient alloimmunization, and nonimmune mechanism in TRALI development among the elderly.

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