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Transfusion-mediated spread of the human T-cell leukemia virus in chronic hemodialysis patients in a heavily endemic area, Nagasaki.

Authors
  • Hino, S
  • Kawamichi, T
  • Funakoshi, M
  • Kanamura, M
  • Kitamura, T
  • Miyamoto, T
Type
Published Article
Journal
Gan
Publication Date
Dec 01, 1984
Volume
75
Issue
12
Pages
1070–1075
Identifiers
PMID: 6098503
Source
Medline
License
Unknown

Abstract

The incidence of anti-adult T-cell leukemia-associated antigens (ATLA) was surveyed in 134 patients under chronic hemodialysis in the Nagasaki area, as well as 4708 blood donors resident in the same area as controls: 23 patients (17%) and 201 donors (4.3%) were positive for anti-ATLA antibody. All seropositive patients were found to have had a positive history of blood transfusions. Seroconversions were confirmed in 9 cases, all of them after initiation of transfusions. In total, 216 units of blood were transfused in 7 seroconverted patients, and this is consistent with the estimated rate of anti-ATLA antibody-positive donor blood supplied by the Red Cross Nagasaki Blood Center (5%).

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