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Transdifferentiation of adipocytes to osteoblasts: potential for orthopaedic treatment.

Authors
  • Lin, Daphne P L1, 2
  • Dass, Crispin R1, 2
  • 1 School of Pharmacy and Biomedical Science, Curtin University, Bentley, Perth, WA, Australia. , (Australia)
  • 2 Curtin Biosciences Research Precinct, Bentley, Perth, WA, Australia. , (Australia)
Type
Published Article
Journal
The Journal of pharmacy and pharmacology
Publication Date
Mar 01, 2018
Volume
70
Issue
3
Pages
307–319
Identifiers
DOI: 10.1111/jphp.12862
PMID: 29365349
Source
Medline
Keywords
License
Unknown

Abstract

Furthermore, due to the possibility of a novel therapy in the treatment of bone conditions, a number of agents with the potential to induce adipo-to-osteoblast transdifferentiation have been investigated such as all-trans retinoic acid, bone morphogenetic protein-9 and vascular endothelial growth factor.

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