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Transcutaneous electrical nerve stimulation for pain during propofol injection: a randomized clinical trial

Authors
  • Lee, Dongwoo1
  • Jin, Juhwa1
  • Kim, Ji Hyo1
  • Oh, Jinyoung1
  • Jeon, Younghoon1
  • 1 .
Type
Published Article
Journal
Journal of Dental Anesthesia and Pain Medicine
Publisher
The Korean Dental Society of Anesthsiology
Publication Date
Nov 24, 2022
Volume
22
Issue
6
Pages
437–442
Identifiers
DOI: 10.17245/jdapm.2022.22.6.437
PMID: 36601133
PMCID: PMC9763824
Source
PubMed Central
Keywords
Disciplines
  • Original Article
License
Unknown

Abstract

Background Propofol is a short-acting intravenous sedative widely used for procedural sedation and general anesthesia. However, pain during propofol injection is a distressing adverse effect. This study was designed to investigate whether transcutaneous electrical nerve stimulation (TENS) could reduce pain during propofol injection compared to sham TENS. Methods In a randomized controlled trial, 80 patients were allocated to two groups: the active TENS group received electrical stimulation via two electrodes on the venous cannulation site, whereas the sham TENS group received no stimulus. After 20 min following TENS, propofol 0.5 mg/kg pain was injected intravenously and pain was evaluated using a four-point score (0 = none, 1 = mild, 2 = moderate, 3 = severe). Adverse effects associated with TENS were also recorded. Results The overall incidence of pain during propofol injection was 47.5% in the TENS group and 87.5% in the sham group (P < 0.001). The incidence of moderate pain was significantly lower in the TENS group (7.5%) than in the sham TENS group (42.5%) (P < 0.001). There were no complications associated with TENS. Conclusion Pre-treatment with TENS significantly reduced the incidence and intensity of pain during propofol injection.

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