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Recent Advances in Mycotoxin Determination for Food Monitoring via Microchip.

Authors
  • 1 Beijing Research Center for Agricultural Standards and Testing, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China. [email protected] , (China)
  • 2 Risk Assessment Lab for Agro-products, Ministry of Agriculture of the People's Republic of China, Beijing 100125, China. [email protected] , (China)
  • 3 Beijing Municipal Key Laboratory of Agriculture Environment Monitoring, Beijing 100097, China. [email protected] , (China)
  • 4 Beijing Research Center for Agricultural Standards and Testing, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China. [email protected] , (China)
  • 5 Risk Assessment Lab for Agro-products, Ministry of Agriculture of the People's Republic of China, Beijing 100125, China. [email protected] , (China)
  • 6 Beijing Municipal Key Laboratory of Agriculture Environment Monitoring, Beijing 100097, China. [email protected] , (China)
  • 7 Beijing Research Center for Agricultural Standards and Testing, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China. [email protected] , (China)
  • 8 Risk Assessment Lab for Agro-products, Ministry of Agriculture of the People's Republic of China, Beijing 100125, China. [email protected] , (China)
  • 9 Beijing Municipal Key Laboratory of Agriculture Environment Monitoring, Beijing 100097, China. [email protected] , (China)
  • 10 Beijing Research Center for Agricultural Standards and Testing, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China. [email protected] , (China)
  • 11 Risk Assessment Lab for Agro-products, Ministry of Agriculture of the People's Republic of China, Beijing 100125, China. [email protected] , (China)
  • 12 Beijing Municipal Key Laboratory of Agriculture Environment Monitoring, Beijing 100097, China. [email protected] , (China)
Type
Published Article
Journal
Toxins
Publisher
MDPI AG
Publication Date
Oct 14, 2017
Volume
9
Issue
10
Identifiers
DOI: 10.3390/toxins9100324
PMID: 29036884
Source
Medline
Keywords
License
Unknown

Abstract

Mycotoxins are one of the main factors impacting food safety. Mycotoxin contamination has threatened the health of humans and animals. Conventional methods for the detection of mycotoxins are gas chromatography (GC) or liquid chromatography (LC) coupled with mass spectrometry (MS), or enzyme-linked immunosorbent assay (ELISA). However, all these methods are time-consuming, require large-scale instruments and skilled technicians, and consume large amounts of hazardous regents and solvents. Interestingly, a microchip requires less sample consumption and short analysis time, and can realize the integration, miniaturization, and high-throughput detection of the samples. Hence, the application of a microchip for the detection of mycotoxins can make up for the deficiency of the conventional detection methods. This review focuses on the application of a microchip to detect mycotoxins in foods. The toxicities of mycotoxins and the materials of the microchip are firstly summarized in turn. Then the application of a microchip that integrates various kinds of detection methods (optical, electrochemical, photo-electrochemical, and label-free detection) to detect mycotoxins is reviewed in detail. Finally, challenges and future research directions in the development of a microchip to detect mycotoxins are previewed.

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