Transcriptional networking

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Transcriptional networking

Publisher
BioMed Central
Publication Date
Jan 01, 2005
Source
PMC
Keywords
Disciplines
  • Biology
  • Computer Science
License
Unknown

Abstract

Genome Biology 2005, 6:344 co m m ent review s repo rts depo sited research interactio ns info rm atio n refereed research Meeting report Transcriptional networking Sarah A Teichmann*, Erich Bornberg-Bauer† and Nicholas M Luscombe‡ Addresses: * Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, UK. †School of Biological Sciences, The Westfalian Wilhelms University of Münster, Botanical Institute, 48149 Münster, Germany. ‡EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SD, UK. Correspondence: Sarah A Teichmann. E-mail: [email protected] Published: 31 August 2005 Genome Biology 2005, 6:344 (doi:10.1186/gb-2005-6-9-344) The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2005/6/9/344 © 2005 BioMed Central Ltd A report on the European Science Foundation workshop ‘Transcription Networks: A Global View’, Madrid, Spain, 26-28 May 2005. The European Science Foundation (ESF) workshop on tran- scriptional regulatory networks held in Madrid this spring, and sponsored by the ESF Programme for Integrated Approaches for Functional Genomics [http://www.functionalgenomics. org.uk/sections/programme], focused on the theme of tran- scriptional regulation in the broadest sense. Topics pre- sented ranged from theoretical approaches to experimental work, and from small systems to studies on many thousands of transcriptional regulatory interactions. The small size of the meeting allowed for ample discussion, which provided a lively atmosphere of scientific dialog. To describe a transcrip- tional regulatory network, one first needs to know which regions of the genome are transcribed. Roderic Guigó (Centre de Regulacio Genomica, Barcelona, Spain) presented the current status of gene annotation in the human genome. Although the genome sequence itself is now very accurate, our knowledge of the number, location and splice

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