Affordable Access

Trajectories of PTSD and Substance Use Disorders in a Longitudinal Study of Personality Disorders.

Authors
  • McDevitt-Murphy, Meghan E1
  • Parra, Gilbert R1
  • Grilo, Carlos M2
  • McGlashan, Thomas H2
  • Skodol, Andrew E3
  • Shea, M Tracie4
  • Yen, Shirley5
  • Sanislow, Charles A6
  • Gunderson, John G7
  • Markowitz, John C8
  • 1 Department of Psychology, The University of Memphis.
  • 2 Department of Psychiatry, Yale University School of Medicine.
  • 3 Department of Psychiatry, University of Arizona College of Medicine and the Sunbelt Collaborative.
  • 4 Veterans' Affairs Medical Center and Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University.
  • 5 Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University.
  • 6 Department of Psychology, Wesleyan University.
  • 7 Department of Psychiatry, Harvard University Medical School and McLean Hospital.
  • 8 Department of Psychiatry, Columbia University and New York State Psychiatric Institute.
Type
Published Article
Journal
Psychological Trauma Theory Research Practice and Policy
Publisher
American Psychological Association
Publication Date
Dec 01, 2009
Volume
1
Issue
4
Pages
269–281
Identifiers
PMID: 26366249
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

This study investigated the co-occurrence of posttraumatic stress disorder (PTSD) and substance use disorders (SUDs) in a sample (N = 668) recruited for personality disorders and followed longitudinally as part of the Collaborative Longitudinal Personality Disorders Study. The study both examined rates of co-occurring disorders at baseline and temporal relationships between PTSD and substance use disorders over 4 years. Subjects with a lifetime history of PTSD at baseline had significantly higher rates of SUDs (both alcohol and drug) than subjects without PTSD. Latent class growth analysis, a relatively novel approach used to analyze trajectories and identify homogeneous subgroups of participant on the basis of probabilities of PTSD and SUD over time, identified 6 classes, which were compared with respect to a set of functioning and personality variables. The most consistent differences were observed between the group that displayed low probabilities of both SUD and PTSD and the group that displayed high probabilities of both.

Report this publication

Statistics

Seen <100 times