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Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review

Authors
  • Ahmad, Mubarak Hussaini1, 2
  • Jatau, Abubakar Ibrahim3
  • Khalid, Garba M.4, 5
  • Alshargi, Omar Yahya6
  • 1 Ahmadu Bello University, Zaria, Nigeria , Zaria (Nigeria)
  • 2 Aminu Dabo College of Health Sciences and Technology, Kano, Nigeria , Kano (Nigeria)
  • 3 University of Tasmania, Hobart, Tas, 7005, Australia , Hobart (Australia)
  • 4 Bayero University, Kano, P.M.B. 3011, Nigeria , Kano (Nigeria)
  • 5 Università degli Studi di Milano, Via G. Colombo, 71, Milan, 20133, Italy , Milan (Italy)
  • 6 Riyadh Elm University, Qurtoba 11681, Riyadh, Saudi Arabia , Riyadh (Saudi Arabia)
Type
Published Article
Journal
Future Journal of Pharmaceutical Sciences
Publisher
Springer Berlin Heidelberg
Publication Date
Jan 14, 2021
Volume
7
Issue
1
Identifiers
DOI: 10.1186/s43094-020-00168-1
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundThe plant Cochlospermum tinctorium A. Rich is a sub-shrub that belongs to the family Cochlospermaceae. The plant has been used in traditional medicine for the treatment of malaria, rickets, stomachache, diarrhea, gastric ulcer, parasitic infestations, liver diseases, fever, pain, inflammation, infectious diseases, epilepsy, snake bite, burns, orchitis, labour, menstrual problems, and many other diseases. This review summarizes the traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium.Main textTo date, few bioactive molecules have been identified and isolated from the plant such as 7,3-dimethyldihydroquercelin, 5,4-dimethylquercelin, cochloxanthine, dihydrocochloxanthine, arjunolic acid, 3-O-E-p-coumaroylalphitolic acid, alphitolic acid, 1-hydroxytetradecan-3-one, 3-bisabolen, 2-tridecanone, 3-hexadecanone, 1-dodecanol, l-tetradecanol, 2-pentdecanone, 3-octadecanone, 1-hydroxy-3-hexadecanone, 1-nonadecanol, l-O-acetyl-3-hexadecanone, and l-hydroxy-3-oetadecanone. The literature related some of the reported ethnomedicinal uses of the plant to these compounds found in the different parts of the plant.ConclusionThe comprehensive information documented in this review about the importance of the C. tinctorium may provide an opportunity for research advancement in drug discovery and a better understanding of the medicinal benefits of the plant.

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