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Tracing skin aging process: a mini- review of in vitro approaches.

Authors
  • Letsiou, Sophia1
  • 1 Laboratory of Biochemistry, Research and Development Department, APIVITA S.A., Industrial Park of Markopoulo Mesogaias, Markopoulo Attiki, 19003, Athens, Greece. [email protected] , (Greece)
Type
Published Article
Journal
Biogerontology
Publication Date
Mar 15, 2021
Identifiers
DOI: 10.1007/s10522-021-09916-z
PMID: 33721158
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Skin is a rather complex, yet useful organ of our body. Besides, skin aging is a complicated process that gains a growing interest as mediates many molecular processes in our body. Thus, an efficient skin model is important to understand skin aging function as well as to develop an effective innovative product for skin aging treatment. In this mini review, we present in vitro methods for assessments of skin aging in an attempt to pinpoint basic molecular mechanisms behind this process achieving both a better understanding of aging function and an effective evaluation of potential products or ingredients that counteract aging. Specifically, this study presents in vitro assays such as 2D or 3D skin models, to evaluate skin aging-related processes such as skin moisturization, photoaging, wound healing, menopause, and skin microbiome as novel efforts in the designing of efficacy assessments in the development of skincare products.

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