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Trabecular Bone Score in Obese and Non-obese Subjects with Primary Hyperparathyroidism Before and After Parathyroidectomy.

Authors
  • Donovan Tay, Yu-Kwang1, 2, 3
  • Cusano, Natalie E1
  • Rubin, Mishaela R1
  • Williams, John1
  • Omeragic, Beatriz1
  • Bilezikian, John P1
  • 1 Department of Medicine, Division of Endocrinology, College of Physicians & Surgeons, Columbia University, New York, NY, USA.
  • 2 Department of Medicine, Sengkang Health, Singapore. , (Singapore)
  • 3 Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Singapore. , (Singapore)
Type
Published Article
Journal
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Publication Date
Jan 24, 2018
Identifiers
DOI: 10.1210/jc.2017-02169
PMID: 29373705
Source
Medline
License
Unknown

Abstract

The detrimental effect of obesity on TBS, an index of bone quality, was demonstrated in subjects with PHPT. Obesity was associated with fully degraded skeletal microarchitecture as measured by TBS in PHPT, despite similar values in bone density by DXA compared to non-obese subjects. TBS values did not improve post-parathyroidectomy in either obese or non-obese subjects.

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