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[Toxic hepatitis associated with Polygoni multiflori].

Authors
  • Bae, Sang Hoon1
  • Kim, Dong Hyun
  • Bae, Young Seok
  • Lee, Kwang Jae
  • Kim, Dong Wan
  • Yoon, Jeoung Bin
  • Hong, Joon Ho
  • Kim, Sang Hyun
  • 1 Department of Internal Medicine, Good Samsun Hospital, Korea. [email protected] , (North Korea)
Type
Published Article
Journal
The Korean journal of hepatology
Publication Date
Jun 01, 2010
Volume
16
Issue
2
Pages
182–186
Identifiers
DOI: 10.3350/kjhep.2010.16.2.182
PMID: 20606503
Source
Medline
License
Unknown

Abstract

Toxic hepatitis has been reported as a major cause of acute hepatitis, but its potential induction by herbal remedies and/or health foods is usually neglected. We experienced a case of toxic hepatitis associated with Polygoni multiflori, a Chinese herb commonly known as Ho-Shou-Wu. A 54-year-old woman consumed Ho-Shou-Wu for 1 month, after which she experienced fatigue and overall weakness. A diagnosis of toxic hepatitis was made based on her clinical history, the findings for viral markers and other laboratory data, and ultrasonography. Her condition improved considerably after she stopped taking Ho-Shou-Wu. However, she resumed taking Ho-Shou-Wu immediately after discharge from hospital, which aggravated her symptoms and liver function. She was immediately readmitted and stopped taking Ho-Shou-Wu. Her relapse into hepatitis immediate after resuming consumption of the herb is strongly indicative of the validity of Koch's postulate in this case.

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