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Toxic fatty acid resistant mutant of Trichophyton rubrum.

Authors
Type
Published Article
Journal
Acta microbiologica Polonica
Publication Date
Volume
26
Issue
4
Pages
403–406
Identifiers
PMID: 75669
Source
Medline
License
Unknown

Abstract

A mutant of Trichophyton rubrum which could tolerate high concentration (110 microgram/ml) of undecanoic acid was isolated from undecanoic (27.5 microgram/ml) sensitive parent. The mutant showed cross resistance towards other fatty acids like propionic acid, caprylic acid and undecenoic acid which were toxic for the parent strain. Development of fatty acid resistance in the mutant strain was associated with increased pigment production. There was no difference in colony or cell morphology between fatty acid resistant mutant and fatty acid sensitive parent.

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