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Total synthesis and complete stereostructure of gambieric acid A.

Authors
  • Fuwa, Haruhiko
  • Ishigai, Kazuya
  • Hashizume, Keisuke
  • Sasaki, Makoto
Type
Published Article
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society
Publication Date
Jul 25, 2012
Volume
134
Issue
29
Pages
11984–11987
Identifiers
DOI: 10.1021/ja305864z
PMID: 22779404
Source
Medline
License
Unknown

Abstract

Total synthesis of gambieric acid A, a potent antifungal polycyclic ether metabolite, has been accomplished for the first time, which firmly established the complete stereostructure of this natural product.

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