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A Toolkit of Engineered Recombinational Balancers in C. elegans.

Authors
  • Schwartz, Hillel T1
  • Sternberg, Paul W2
  • 1 Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • 2 Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: [email protected]
Type
Published Article
Journal
Trends in Genetics
Publisher
Elsevier
Publication Date
Apr 01, 2018
Volume
34
Issue
4
Pages
253–255
Identifiers
DOI: 10.1016/j.tig.2018.01.009
PMID: 29395380
Source
Medline
Keywords
License
Unknown

Abstract

Dejima and colleagues report using CRISPR/Cas9 to generate a new collection of greatly improved balancer chromosomes in the standard laboratory nematode Caenorhabditis elegans, using methods previously reported by the same laboratory, expanding the set of C. elegans balancers to cover nearly 90% of coding genes.

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