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Tolvaptan improves left ventricular dysfunction after myocardial infarction in rats.

Authors
  • Yamazaki, Takanori
  • Izumi, Yasukatsu
  • Nakamura, Yasuhiro
  • Yamashita, Naoto
  • Fujiki, Hiroyuki
  • Osada-Oka, Mayuko
  • Shiota, Masayuki
  • Hanatani, Akihisa
  • Shimada, Kenei
  • Iwao, Hiroshi
  • Yoshiyama, Minoru
Type
Published Article
Journal
Circulation Heart Failure
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Nov 01, 2012
Volume
5
Issue
6
Pages
794–802
Identifiers
DOI: 10.1161/CIRCHEARTFAILURE.112.968750
PMID: 22984091
Source
Medline
License
Unknown

Abstract

Tolvaptan may improve cardiac dysfunction after MI, which is partially mediated by the suppression of V(1a) receptor, neurohumoral activation and inflammation.

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