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Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies.

Authors
Type
Published Article
Journal
Annals of the rheumatic diseases
Publication Date
Volume
66
Issue
10
Pages
1327–1333
Identifiers
PMID: 17261530
Source
Medline

Abstract

These findings in LPS-/- mice and the reduction in the "protective" polymorphism in patients with APS with thrombosis suggest that TLR-4 is involved in the interaction of aPL with endothelial cells in vivo.

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