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TNF-alpha and shear stress-induced large artery adaptations.

Authors
  • Ozaki, C Keith
  • Jiang, Zhihua
  • Berceli, Scott A
Type
Published Article
Journal
The Journal of surgical research
Publication Date
Aug 01, 2007
Volume
141
Issue
2
Pages
299–305
Identifiers
PMID: 17574273
Source
Medline
License
Unknown

Abstract

Shear stress differentially and temporally regulates TNF-alpha expression in remodeling large arteries. However, TNF-alpha blockage did not substantially impact the final shear-induced morphology, suggesting that large arteries can remodel in response to flow perturbations independent of TNF-alpha signaling.

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