Affordable Access

Access to the full text

Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage

Authors
  • Hajjari, Mohammadreza
  • Sadeghi, Iman
  • Abbas Salavaty
  • Nasiri, Habib
  • Birgani, Maryam Tahmasebi
Type
Published Article
Journal
Genomics & Informatics
Publisher
Korea Genome Organization
Publication Date
Jan 25, 2016
Volume
14
Identifiers
DOI: 10.5808/gi.2016.14.4.234
Source
MyScienceWork
License
Green

Abstract

Different mechanisms, including transcriptional and post transcriptional processes, regulate tissue specific expression of genes. In this study, we report differences in gene/protein compositional features between apoptosis involved genes selectively expressed in human tissues. We found some correlations between codon/amino acid usage and tissue specific expression level of genes. The findings can be significant for understanding the translational selection on these features. The selection may play an important role in the differentiation of human tissues and can be considered for future studies in diagnosis of some diseases such as cancer.

Report this publication

Statistics

Seen <100 times