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Tissue microarray-based study of patients with lymph node-negative breast cancer shows that HER2/neu overexpression is an important predictive marker of poor prognosis.

Authors
  • Choi, Y H
  • Ahn, J H
  • Kim, S-B
  • Jung, K-H
  • Gong, G-Y
  • Kim, M-J
  • Son, B-H
  • Ahn, S-H
  • Kim, W K
Type
Published Article
Journal
Annals of Oncology
Publisher
Oxford University Press
Publication Date
Aug 01, 2009
Volume
20
Issue
8
Pages
1337–1343
Identifiers
DOI: 10.1093/annonc/mdp003
PMID: 19221151
Source
Medline
License
Unknown

Abstract

Our results show that HER2/neu overexpression is an important independent prognostic factor for LN-negative breast cancer cases and support the theory that more intensive adjuvant chemotherapy is required in the population with HER2/neu overexpression.

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