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Tissue factor induces human coronary artery smooth muscle cell motility through Wnt-signalling.

Authors
Type
Published Article
Journal
Journal of thrombosis and haemostasis : JTH
Publication Date
Volume
11
Issue
10
Pages
1880–1891
Identifiers
DOI: 10.1111/jth.12327
PMID: 23782925
Source
Medline
Keywords
  • Wnt Signaling Pathway
  • Atherosclerosis
  • Coronary Artery
  • Thrombosis
  • Tissue Factor

Abstract

The 'in silico' analysis pointed to specific Wnt-pathway proteins that have been validated in cell culture and also have been found expressed in human advanced atherosclerotic plaques but not in early lesions. TF signals through Wnt to regulate coronary smooth muscle cell migration and vascular remodeling.

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