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Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia

Authors
  • Han, Fengxuan1, 2
  • Wang, Jiayuan1, 2
  • Ding, Luguang1, 2
  • Hu, Yuanbin3
  • Li, Wenquan4
  • Yuan, Zhangqin1, 2
  • Guo, Qianping1, 2
  • Zhu, Caihong1, 2
  • Yu, Li1, 2
  • Wang, Huan1, 2
  • Zhao, Zhongliang1, 2
  • Jia, Luanluan1, 2
  • Li, Jiaying1, 2
  • Yu, Yingkang1, 2
  • Zhang, Weidong1, 2
  • Chu, Genglei1
  • Chen, Song1, 2
  • Li, Bin1, 2, 5
  • 1 Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou , (China)
  • 2 Orthopaedic Institute, Soochow University, Suzhou , (China)
  • 3 Department of Orthopaedics, Zhongda Hospital, Southeast University, Nanjing , (China)
  • 4 Department of Otolaryngology, The Second Affiliated Hospital of Soochow University, Suzhou , (China)
  • 5 China Orthopedic Regenerative Medicine Group (CORMed), Hangzhou , (China)
Type
Published Article
Journal
Frontiers in Bioengineering and Biotechnology
Publisher
Frontiers Media SA
Publication Date
Mar 24, 2020
Volume
8
Identifiers
DOI: 10.3389/fbioe.2020.00083
PMID: 32266221
PMCID: PMC7105900
Source
PubMed Central
Keywords
License
Unknown

Abstract

Exploring innovative solutions to improve the healthcare of the aging and diseased population continues to be a global challenge. Among a number of strategies toward this goal, tissue engineering and regenerative medicine (TERM) has gradually evolved into a promising approach to meet future needs of patients. TERM has recently received increasing attention in Asia, as evidenced by the markedly increased number of researchers, publications, clinical trials, and translational products. This review aims to give a brief overview of TERM development in Asia over the last decade by highlighting some of the important advances in this field and featuring major achievements of representative research groups. The development of novel biomaterials and enabling technologies, identification of new cell sources, and applications of TERM in various tissues are briefly introduced. Finally, the achievement of TERM in Asia, including important publications, representative discoveries, clinical trials, and examples of commercial products will be introduced. Discussion on current limitations and future directions in this hot topic will also be provided.

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