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Thyroid-stimulating immunoglobulins and the control of thyroid function.

Authors
Type
Published Article
Journal
The Journal of clinical endocrinology and metabolism
Publication Date
Volume
43
Issue
3
Pages
550–556
Identifiers
PMID: 821961
Source
Medline
License
Unknown

Abstract

Triiodothyronine (T3) suppression and thyrotropin-releasing hormone (TRH) tests were used to study thyroid function in 50 patients with thyroid disease. The results of the thyroid function tests were compared with the levels of serum thyroid-stimulating immunoglobulins (TSI) measured by a radio-receptor assay. In euthyroid and hyperthyroid patients, the presence of TSI corresponded with the absence of TSH control of thyroid function. However, in two hypothyroid patients with serum TSI levels readily detectable in the receptor assay, T3 suppression and TRH tests indicated that thyroid function was under TSH control.

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