Thymoma-associated exfoliative dermatitis in a goat: case report and brief literature review.
Departments of Microbiology, Immunology, and Pathology (Byas, Frank), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO.
Clinical Sciences (Applegate, Stuart), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO.
Department of Large Animal Medicine and Surgery, School of Veterinary Medicine, St. George's University, True Blue, Grenada, West Indies, Grenada (Byers).
- Published Article
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Publication Date
Nov 01, 2019
A Rock Alpine doe (Capra aegagrus hircus) was presented to the Colorado State University Veterinary Teaching Hospital because of scaling and ulceration over the withers, coronary bands, and dewclaws. The doe was euthanized because of poor prognosis associated with a radiographically identified cranial mediastinal mass, increased respiratory effort, and discomfort. Autopsy revealed a cranial mediastinal mass, and scaling-to-ulcerative lesions affecting the dorsum, ventrum, pinna, neck, teats, coronary bands, and dewclaws. Histologically, the mediastinal mass was an epithelial neoplasm with admixed non-neoplastic T lymphocytes, consistent with a lymphoepithelial (mixed) thymoma. Sections of affected skin were characterized by hyperkeratotic cell-rich interface dermatitis with transepidermal and follicular apoptosis. Thymoma-associated exfoliative dermatitis has been recognized in cats and a rabbit, but has not been reported previously in a goat, to our knowledge. Given that thymomas are not uncommon in goats, thymoma-associated exfoliative dermatitis should be considered a clinical differential in goats with dermatologic disease.
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This record was last updated on 11/12/2020 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/31650897