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Thrombin generation in patients with idiopathic sudden sensorineural hearing loss.

Authors
  • Tripodi, Armando1
  • Capaccio, Pasquale2
  • Pignataro, Lorenzo3
  • Chantarangkul, Veena4
  • Menegatti, Marzia5
  • Bamonti, Fabrizia6
  • Clerici, Marigrazia4
  • De Giuseppe, Rachele6
  • Peyvandi, Flora5
  • 1 Angelo Bianchi Bonomi, Hemophilia and Thrombosis Center, Department of Clinical Sciences and Community Health, Università degli Studi di Milano and IRCCS Cà Granda Maggiore Hospital Foundation, Milano, Italy. Electronic address: [email protected] , (Italy)
  • 2 Department of Biomedical, Surgical and Dental Sciences, University of Milan, Università degli Studi di Milano and IRCCS Cà Granda Maggiore Hospital Foundation, Milano, Italy. , (Italy)
  • 3 Department of Clinical Sciences and Community Health, Università degli Studi di Milano and IRCCS Cà Granda Maggiore Hospital Foundation, Milano, Italy. , (Italy)
  • 4 Angelo Bianchi Bonomi, Hemophilia and Thrombosis Center, Department of Clinical Sciences and Community Health, Università degli Studi di Milano and IRCCS Cà Granda Maggiore Hospital Foundation, Milano, Italy. , (Italy)
  • 5 Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Pathophysiology and Transplantation, Università degli Studi di Milano and IRCCS Ca' Granda Maggiore Hospital Foundation, Milano, Italy. , (Italy)
  • 6 Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Department of Hematology-Oncology and BMT Unit, IRCCS Cà Granda Maggiore Hospital Foundation, Milan, Italy. , (Italy)
Type
Published Article
Journal
Thrombosis research
Publication Date
Jun 01, 2014
Volume
133
Issue
6
Pages
1130–1134
Identifiers
DOI: 10.1016/j.thromres.2014.03.031
PMID: 24690481
Source
Medline
Keywords
License
Unknown

Abstract

The results suggest that the pathogenesis of ISSNHL is not due to systemic blood hypercoagulability. Other culprits such as local vascular abnormalities, viral infections, immune-mediated mechanisms or abnormalities of inner ear and central nervous system should be advocated to explain ISSNHL.

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