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Three-dimensional drip infusion CT cholangiography in patients with suspected obstructive biliary disease: a retrospective analysis of feasibility and adverse reaction to contrast material.

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BioMed Central
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PMC
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  • Research Article
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  • Medicine

Abstract

1471-2342-6-1.fm ral ss BioMed CentBMC Medical Imaging Open AcceResearch article Three-dimensional drip infusion CT cholangiography in patients with suspected obstructive biliary disease: a retrospective analysis of feasibility and adverse reaction to contrast material. A Persson*1, N Dahlström2, Ö Smedby1 and TB Brismar3 Address: 1Center for Medical Image Science and Visualization (CMIV), Linköping University Hospital, Sweden, 2Department of Radiology, Hudiksvall Hospital, Sweden and 3Division of Radiology, Karolinska Institutet, Sweden Email: A Persson* - [email protected]; N Dahlström - [email protected]; Ö Smedby - [email protected]; TB Brismar - [email protected] * Corresponding author Abstract Background: Computed Tomography Cholangiography (CTC) is a fast and widely available alternative technique to visualise hepatobiliary disease in patients with an inconclusive ultrasound when MRI cannot be performed. The method has previously been relatively unknown and sparsely used, due to concerns about adverse reactions and about image quality in patients with impaired hepatic function and thus reduced contrast excretion. In this retrospective study, the feasibility and the frequency of adverse reactions of CTC when using a drip infusion scheme based on bilirubin levels were evaluated. Methods: The medical records of patients who had undergone upper abdominal spiral CT with subsequent three-dimensional rendering of the biliary tract by means of CTC during seven years were retrospectively reviewed regarding serum bilirubin concentration, adverse reaction and presence of visible contrast media in the bile ducts at CT examination. In total, 153 consecutive examinations in 142 patients were reviewed. Results: Contrast media was observed in the bile ducts at 144 examinations. In 110 examinations, the infusion time had been recorded in the medical records. Among these, 42 examinations had an elevated bilirubin value (>19 umol/L). There were nin

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